Discover brain health and Alzheimer’s clinical studies
We run a range of studies involving healthy volunteers, people living with Alzheimer’s disease or diagnosed with a mild cognitive impairment, and those concerned about memory or brain health.
Each study has its own purpose and eligibility criteria, but all share one goal — to improve understanding and treatment of brain conditions.
We match people to studies based on the eligibility criteria.
Studies and trials currently recruiting
IONA Longitudinal Cohort Study (Scottish Brain Sciences study)
The IONA LCS study is our own flagship study exploring risk factors and early signs of conditions that can lead to dementia. Participants in our IONA study can be matched to commercial trials.
- Who we’re looking for:
- People aged 65 + with no diagnosis of Alzheimer’s disease or other mild cognitive impairment
- People aged 50+ with a diagnosis of Alzheimer’s or mild cognitive impairment or those with a family history of neurodegenerative disease.
- Study design: Baseline and ongoing biomarker and cognitive testing.
- Length of study: 10 years with an annual visit and 6 monthly telephone check-in.
- Location: Available in Aberdeen and Edinburgh.
Disease-modifying treatments which may help slow disease progression of Alzheimer’s disease dementia.
- Who we’re looking for: People aged 50-90 with a diagnosis of Mild Cognitive Impairment or Early Alzheimer’s Disease.
- Study design: Periodic IV infusions.
- Location: Available in Aberdeen and Edinburgh.
Treatments which may help manage the symptoms of Alzheimer’s disease dementia.
- Who we’re looking for:People aged 55-90 with a diagnosis of Alzheimer’s disease dementia and already taking a prescribed Alzheimer’s medication.
- Study design: Taken as a daily tablet.
- Location: Open in Aberdeen and Edinburgh.
Opening soon: Treatment which may help manage agitation symptoms associated with Alzheimer’s disease dementia.
- Who we’re looking for: People aged 55-90 with a diagnosis of Alzheimer’s who experience agitation as a symptom. Agitation can include a range of behaviours including pacing or wandering, repetitive actions or aggression.
- Study design: Taken as a daily capsule over 8 weeks.
- Location: Opening soon in Aberdeen and Edinburgh.
Opening soon: A treatment to prevent or delay onset of Alzheimer’s disease symptoms in those with no current symptoms or diagnosis.
Eligibility is determined by detection of the early changes that lead to Alzheimer’s disease.
- Who we’re looking for:
- People aged 65-80 with no diagnosis of Alzheimer’s disease
- People aged 55-64 with a parent or sibling with a diagnosis of Alzheimer’s Disease
- People aged 55-64 and are known to possess at least one copy of APOE4 gene
- Location: Opening soon in Aberdeen and Edinburgh.
All our studies are approved by an independent ethics committee and conducted under strict NHS and UK regulatory standards.
Your safety, privacy, and comfort always come first.
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